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中文人类
PTK6 - Protein Tyrosine Kinase 6
Alias:
BRK
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这个基因编码的蛋白质是一种胞质非受体蛋白激酶，可能在上皮组织中作为细胞内信号转导子发挥作用。在乳腺上皮细胞中过度表达该基因会导致细胞对表皮生长因子敏感，并导致部分转化表型。该基因在某些乳腺癌肿瘤中低水平表达，而在正常乳腺组织中不表达。编码的蛋白质已经显示可以进行自磷酸化。可变剪接导致多个转录变异体。[RefSeq, 2012年1月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
PTK6 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
