Log In|Sign Up
中文人类
PTK2 - Protein Tyrosine Kinase 2
Alias:
FAK
FADK
FAK1
FRNK
FADK 1
PPP1R71
p125FAK
pp125FAK
Favorite
这个基因编码一个在细胞质中浓集的蛋白质酪氨酸激酶，存在于细胞与细胞外基质成分共同生长时形成的粘附斑中。编码的蛋白质是FAK酪氨酸激酶亚家族的一员，但与来自其他亚家族的激酶的序列相似性不高。这个基因的激活可能是细胞生长和细胞内信号传导途径中早期的重要步骤，这些途径响应某些神经肽或细胞与细胞外基质的相互作用而被触发。已经发现这个基因的几个转录变异体，编码不同的异构体。[RefSeq,2017年6月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
PTK2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
