人类

PTGS2 - Prostaglandin-endoperoxide Synthase 2

Alias:
COX2
COX-2
PHS-2
PGG/HS
PGHS-2
hCox-2
GRIPGHS
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
前列腺素内过氧化物合酶(PTGS),也称为环加氧酶,是前列腺素生物合成中的关键酶,既作为二氧酶又作为过氧化物酶发挥作用。PTGS有两个同工酶:构成性的PTGS1和诱导性的PTGS2,它们的表达调控和组织分布不同。这个基因编码诱导性同工酶。它受到特定刺激事件的调控,表明它负责前列腺素生物合成,涉及炎症和细胞有丝分裂。[RefSeq,2009年2月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1
10
8633 bp
69.00
23
--
18
31

PTGS2 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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