Log In|Sign Up
中文人类
PTGIS - Prostaglandin I2 Synthase
Alias:
CYP8
PGIS
PTGI
CYP8A1
Favorite
这个基因编码细胞色素P450超家族酶的一员。细胞色素P450蛋白是单加氧酶，催化许多与药物代谢和胆固醇、类固醇和其他脂质合成有关的反应。然而，这个蛋白质被认为是细胞色素P450超家族的一员，主要是基于序列相似性而不是功能相似性。这个内质网膜蛋白催化前列腺素H2向前列腺环素（前列腺素I2）的转化，前列腺环素是一种强效的血管舒张剂和血小板聚集抑制剂。前列腺环素的生理拮抗剂血栓素A2失衡有助于心肌梗死、中风和动脉粥样硬化的发展。[RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
PTGIS Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
