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中文人类
PTGER4 - Prostaglandin E Receptor 4
Alias:
EP4
EP4R
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这个基因编码的蛋白质是G-蛋白偶联受体家族的成员。这种蛋白质是已知的四种前列腺素E2（PGE2）受体之一。这种受体可以激活T细胞因子信号传导。已经证明它可以调节环氧化酶-2 mRNA的水平稳定性和早期生长反应1（EGR1）的表达，并导致糖原合成酶激酶-3的磷酸化。小鼠的敲除研究表明，这个受体可能参与循环系统的新生儿适应、骨质疏松和皮肤免疫反应的启动。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
PTGER4 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
