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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Brd4 - bromodomain containing 4
Alias:
Brd5
MCAP
HUNK1
WI-11513
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有多种功能,包括RNA聚合酶II C端域结合活性;染色质结合活性;和蛋白丝氨酸/苏氨酸激酶活性。在几个过程的上游或内部发挥作用,包括组蛋白乙酰化;内细胞团细胞增殖;和蛋白自磷酸化。位于染色质和浓缩的核染色体中。是细胞周期蛋白/CDK正转录延长因子复合物的一部分。在几个结构中表达,包括中枢神经系统;背根神经节;早期胎囊;生殖泌尿系统;和视网膜。此基因的人类同源物与结肠癌和特发性肺纤维化有关。与人类BRD4(含bromodomain 4)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:57261
ENSEMBL:ENSMUSG00000024002
UNIPROT:Q9ESU6
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
57261
34
20
88472 bp
155.90
8
19
Brd4 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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Transcript
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* This data comes from NCBI.
Gene Expression
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