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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
PSMD10 - Proteasome 26S Subunit, Non-ATPase 10
Alias:
p28
p28(GANK)
dJ889N15.2
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码PA700/19S复合物的亚基,该复合物是26S蛋白酶体的调节成分。26S蛋白酶体复合物是泛素依赖性蛋白质降解所必需的。这个蛋白质是一个非ATP酶亚基,可能涉及蛋白质-蛋白质相互作用。这个基因的异常表达可能在肿瘤发生中发挥作用。已经描述了两个编码不同异构体的转录本。在染色体3和20上已经发现了假基因。[RefSeq,2011年3月提供]
Related ID:
NCBI:5716
ENSEMBL:ENSG00000101843
HGNC:9555
UNIPROT:O75832
OMIM:300880
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
5716
2
5
7336 bp
24.43
6
--
4
17
PSMD10 Genetics information (-)
GRCh38
Sequence Homology
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* This data comes from NCBI.
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