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中文人类
CD177 - CD177 Molecule
Alias:
NB1
PRV1
HNA2A
PRV-1
HNA-2a
NB1 GP
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这个基因编码一个糖基-磷酯酰肌醇(GPI)连接的细胞表面糖蛋白，在嗜中性粒细胞的激活中起作用。该蛋白可以结合血小板内皮细胞粘附分子-1，并在嗜中性粒细胞的迁移中发挥作用。这个基因的突变与骨髓增生性疾病有关。在真性红细胞过多症患者中，这个基因的过度表达被发现有。针对该蛋白的自身抗体可能导致肺转移反应，并且它可能与韦格纳肉芽肿有关。一个与该基因在染色体19上相邻的假基因已经被识别出来。[由RefSeq，2014年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CD177 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
