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Adam17 - ADAM metallopeptidase domain 17

Alias:
TACE
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测能够实现PDZ结构域结合活性;参与淀粉样前体蛋白分解代谢过程的金属内肽酶活性;以及信号受体结合活性。参与几个过程,包括凋亡过程的调节;信号传导的调节;以及对抗肿瘤药物的响应。位于几个细胞组件中,包括细胞的顶部分;细胞表面;和胞质囊泡。阿尔茨海默病的生物标志物;充血性心力衰竭;和胸主动脉瘤。这个基因的人类同源物涉及阿尔茨海默病;炎症性肠病;和2型糖尿病。与人类ADAM17(金属肽酶结构域17)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
2
19
47765 bp
93.02
20
2

Adam17 Genetics information (-)

mRatBN7.2

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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