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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
PSMB4 - Proteasome 20S Subunit Beta 4
Alias:
HN3
HsN3
PRAAS3
PROS26
PROS-26
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
蛋白酶体是一种具有高度有序环状20S核心结构的多催化蛋白酶复合物。核心结构由4个由28个非相同亚基组成的环组成;2个环由7个alpha亚基组成,2个环由7个beta亚基组成。蛋白酶体在真核细胞中以高浓度分布,并在非溶酶途径中,在ATP/泛素依赖的过程中切割肽。修饰过的蛋白酶体,即免疫蛋白酶体,在加工I类MHC肽中起基本作用。此基因编码蛋白酶B型家族的一员,也称为T1B家族,是20S核心beta亚基。[由RefSeq,2008年7月提供]
Related ID:
NCBI:5692
ENSEMBL:ENSG00000159377
HGNC:9541
UNIPROT:P28070
OMIM:602177
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
5692
1
7
2365 bp
29.20
147
3
2
34
PSMB4 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Transcripts & Proteins
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Transcript
Length(nt)
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CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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Type
Name
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Status
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Link
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References Literature
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