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中文人类
RAD18 - RAD18 E3 Ubiquitin Protein Ligase
Alias:
RNF73
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这个基因编码的蛋白质与啤酒酵母DNA损伤修复蛋白Rad18高度相似。酵母Rad18通过与其Rad6相互作用而发挥作用，Rad6是后复制修复受损DNA所需的泛素结合酶。与酵母对应物相似，这个蛋白质能够通过保守的环指结构基序与人类酵母Rad6蛋白的同源物相互作用。这个基序的突变导致UV损伤DNA复制缺陷和对多种诱变剂的超敏感。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
RAD18 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
