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中文人类
SPHK2 - Sphingosine Kinase 2
Alias:
SK 2
SK-2
SPK 2
SPK-2
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这个基因编码两种鞘氨醇激酶同功酶之一，催化鞘氨醇磷酸化成为鞘氨醇1-磷酸。鞘氨醇1-磷酸调节许多细胞过程，包括迁移、增殖和凋亡，并通过促进血管生成和肿瘤发生参与几种类型的癌症。编码的蛋白质可能在乳腺癌增殖和化学抗性中发挥作用。已经观察到这个基因的替代剪接转录变异体编码多种异构体。[RefSeq,2011年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
SPHK2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
