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中文小鼠
Sphk2 - sphingosine kinase 2
Alias:
Sk2
Spk2
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这个基因编码一个激酶，将鞘氨醇磷酸化为鞘氨醇-1-磷酸，参与细胞分化、运动和凋亡。编码的蛋白质在维持鞘氨醇-1-磷酸的细胞水平中发挥作用。基因产物还能增强不同细胞类型的凋亡并抑制细胞增殖。在肥大细胞中，编码的蛋白质对于钙流入、蛋白激酶C激活、细胞因子产生和脱颗粒是必需的。选择性剪接导致多个转录变异体。[RefSeq，2010年2月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Sphk2 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
