人类

PRSS8 - Serine Protease 8

Alias:
CAP1
PROSTASIN
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码丝氨酸蛋白酶肽酶S1或胰凝乳蛋白酶家族的一员。编码的前原蛋白在蛋白水解过程中被处理,生成通过二硫键结合的重链和轻链,形成异源二聚酶。这种酶在前列腺上皮中高度表达,是精液中发现的几种蛋白水解酶之一。这种蛋白酶表现出类似胰蛋白酶的底物特异性,在赖氨酸或精氨酸残基的羧基端切割蛋白质底物。编码的蛋白酶部分介导上皮钠通道的蛋白水解激活,这是一种钠平衡的调节剂,也可能参与上皮屏障的形成。[RefSeq,2016年2月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1
6
4295 bp
36.43
7
--
15
8

PRSS8 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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