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中文小鼠
Rapgef4 - Rap guanine nucleotide exchange factor (GEF) 4
Alias:
Epac2
EPAC 2
Epac-2
mKIAA4040
1300003D15Rik
5730402K07Rik
6330581N18Rik
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激活cAMP结合活性；鸟苷酸交换因子活性；和小GTP酶结合活性。参与突触囊泡周期的调节。在腺苷酸环化酶激活G蛋白偶联受体信号通路中起到上游或内部作用；调节突触外泌体和细胞分泌。位于细胞质和海马苔藓纤维到CA3突触的位置。在几个结构中表达，包括肾上腺；神经节；心脏；肺；和肾单位。这个基因的人类同源物与自闭症有关。与人类的RAPGEF4（Rap鸟苷酸交换因子4）正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Rapgef4 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
