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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Ikbke - inhibitor of kappaB kinase epsilon
Alias:
Ikki
IKK-E
IKK-i
IKKepsilon
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活IkappaB激酶活性;K48链接的多泛素修饰依赖的蛋白质结合活性;以及泛素蛋白连接酶结合活性。参与几个过程,包括白细胞介素-17介导的信号通路;mRNA稳定性;以及I型干扰素介导的信号通路的正向调节。预测位于PML体和线粒体膜上。预测在细胞质中活性。在几个结构中表达,包括未来脑;感器器官;下颌腺原基;胸腺原基;和鼻骨原基。与人类的IBKKE(核因子kappa B激酶抑制子ε)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:56489
ENSEMBL:ENSMUSG00000042349
UNIPROT:Q9R0T8
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
56489
7
22
25003 bp
80.95
7
10
Ikbke Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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