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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Tbk1 - TANK-binding kinase 1
Alias:
1200008B05Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有多种功能,包括相同的蛋白质结合活性;蛋白质磷酸酶结合活性;以及蛋白质丝氨酸/苏氨酸激酶活性。参与基因表达的负调控;肽基丝氨酸磷酸化;以及防御响应的正调控。在几个过程的上游或内部发挥作用,包括对革兰阳性菌的防御响应;树突细胞的增殖;以及正调控干扰素-β的生成。预测位于核质中。预测在细胞质中活跃。在几个结构中表达,包括消化系统;大脑;生殖泌尿系统;呼吸系统;和感觉器官。该基因的人类同源物与脑疾病和前额叶痴呆和/或肌萎缩侧索硬化-4有关。与人类TBK1(TANK结合激酶1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:56480
ENSEMBL:ENSMUSG00000020115
UNIPROT:Q9WUN2
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
56480
1
21
40340 bp
83.42
15
11
Tbk1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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Transcript
Length(nt)
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Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
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Type
Name
MGI
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References Literature
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IF
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