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Adar - adenosine deaminase, RNA-specific

Alias:
Adar1
DRADA
mZaADAR
Adar1p110
Adar1p150
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有双链RNA腺苷脱氨酶活性。参与几个过程,包括腺苷到肌苷的编辑;通过调节蛋白质磷酸化来负调控蛋白激酶活性;以及正调控病毒基因组复制。在几个过程的上游或内部发挥作用,包括造血干细胞稳态;免疫系统发育;以及基因表达的调控。位于细胞质和核仁中。在几个结构中表达,包括消化系统;中枢神经系统;生殖泌尿系统;皮肤系统;和感觉器官。该基因的人类同源物涉及Aicardi-Goutieres综合征;人乳头瘤病毒感染性疾病;遗传性对称性色素减退;和肝硬化。与人类ADAR(腺苷脱氨酶RNA特异性)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
12
15
38436 bp
130.45
30
20

Adar Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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