人类

PRRG1 - Proline Rich And Gla Domain 1

Alias:
PRGP1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一种依赖于维生素K的、含有γ-谷氨酸(Gla)的、单跨膜蛋白。这个蛋白在N端含有Gla结构域,之前是一个前肽序列,该序列在翻译后由维生素K依赖的γ-羧化酶对特定的谷氨酸残基进行γ-羧化。C端富含脯氨酸,含有PPXY和PXXP基序,这些基序在各种信号传导和细胞骨架蛋白中发现。这个基因在脊髓中高度表达。已经发现了这个基因的几个可变剪接转录变异体。[RefSeq,2010年3月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
5
4
107928 bp
24.95
5
--
3
6

PRRG1 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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