Tmeff2 - transmembrane protein with EGF-like and two follistatin-like domains 2

Predicted to be involved in several processes, including animal organ morphogenesis; cell migration; and substrate adhesion-dependent cell spreading. Predicted to act upstream of or within negative regulation of cell migration; negative regulation of cellular component organization; and wound healing, spreading of cells. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in basement membrane and plasma membrane. Is expressed in several structures, including embryo mesenchyme; intestine; and nervous system. Human ortholog(s) of this gene implicated in prostate cancer and urinary bladder cancer. Orthologous to human TMEFF2 (transmembrane protein with EGF like and two follistatin like domains 2). [provided by Alliance of Genome Resources, Apr 2022]