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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
IL36G - Interleukin 36 Gamma
Alias:
IL1E
IL1F9
IL1H1
IL-1F9
IL-1H1
IL1RP2
IL-1RP2
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是白细胞介素1细胞因子家族的一员。这个细胞因子的活性是通过白细胞介素1样受体2(IL1RL2/IL1R-rp2)介导的,并被白细胞介素1家族成员5(IL1F5/IL-1 delta)特异地抑制。据报道,干扰素-γ、肿瘤坏死因子-α和白介素1β(IL1B)可以刺激角质细胞中这个细胞因子的表达。这个细胞因子在角质细胞中的表达还可以由接触性超敏反应或单纯疱疹病毒感染诱导。这个基因和另外8个白细胞介素1家族基因在染色体2上形成一个细胞因子基因簇。[RefSeq提供,2019年5月]
Related ID:
NCBI:56300
ENSEMBL:ENSG00000136688
HGNC:15741
UNIPROT:Q9NZH8
OMIM:605542
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
56300
2
5
7653 bp
18.72
6
--
4
14
IL36G Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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