人类

PROX1 - Prospero Homeobox 1

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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是同源异型DNA结合因子家族的一员。这个家族的成员包含一个同源异型结构域,由一个60个氨基酸的螺旋-转角-螺旋结构组成,可以结合DNA和RNA。这个基因编码的蛋白质在脊椎动物中具有保守性,可能在发育过程中发挥重要作用。据报道,这个蛋白质的水平在不同器官的癌症中发生改变,如结肠、大脑、血液、乳房、胰腺、肝脏和食管。可变剪接导致多个转录变异体。[由RefSeq,2012年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
14
5
58360 bp
83.20
20
--
13
9

PROX1 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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