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中文小鼠
Bace2 - beta-site APP-cleaving enzyme 2
Alias:
ARP1
ASP1
BAE2
DRAP
AEPLC
ALP56
ASP21
CDA13
CEAP1
1110059C24Rik
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这个基因编码肽酶A1家族的成员，该家族属于天冬氨酸蛋白酶。编码的前原蛋白经历蛋白水解过程，生成一种活性内切肽酶。这种跨膜蛋白酶催化淀粉样前体蛋白的蛋白水解，产生淀粉样β肽。缺乏编码产物的小鼠表现出增加的胰腺β细胞质量，以及由于胰岛素分泌增加而改善的葡萄糖耐受性。[由RefSeq，2016年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Bace2 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
