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中文人类
MAP2K7 - Mitogen-activated Protein Kinase Kinase 7
Alias:
MEK
MKK7
JNKK2
MEK 7
MAPKK7
PRKMK7
SAPKK4
SAPKK-4
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这个基因编码的蛋白质是一种属于MAP激酶激酶家族的双向特异性蛋白激酶。这种激酶能特异地激活MAPK8/JNK1和MAPK9/JNK2，并且这种激酶本身可以被包括MAP3K1/MEKK1、MAP3K2/MEKK2、MAP3K3/MEKK5和MAP4K2/GCK在内的MAP激酶激酶磷酸化和激活。这种激酶参与信号传导，调节细胞对前炎症细胞因子和环境压力的反应。可变剪接产生了多种转录变异体。[RefSeq，2014年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
MAP2K7 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
