Set - SET nuclear oncogene

Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in negative regulation of transcription, DNA-templated. Predicted to act upstream of or within negative regulation of neuron apoptotic process. Located in nucleus. Is expressed in several structures, including branchial arch; central nervous system; sensory organ; skin; and tooth. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability. Orthologous to human SET (SET nuclear proto-oncogene). [provided by Alliance of Genome Resources, Apr 2022]