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中文人类
MAP2K6 - Mitogen-activated Protein Kinase Kinase 6
Alias:
MEK6
MKK6
MAPKK6
PRKMK6
SAPKK3
SAPKK-3
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这个基因编码一个双特异性蛋白激酶家族的成员，作为有丝分裂激活蛋白（MAP）激酶激酶发挥作用。MAP激酶，也称为细胞外信号调节激酶（ERKs），作为多个生物化学信号的整合点。这个蛋白对炎症细胞因子或环境压力作出反应，对p38 MAP激酶进行磷酸化并激活。作为p38 MAP激酶介导的信号传导途径的必备组件，这个基因参与许多细胞过程，如应激诱导的细胞周期停滞、转录激活和凋亡。[由RefSeq提供，2008年7月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
MAP2K6 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
