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中文人类
MAP2K5 - Mitogen-activated Protein Kinase Kinase 5
Alias:
MEK5
MAPKK5
PRKMK5
HsT17454
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这个基因编码的蛋白质是一种属于MAP激酶激酶家族的双向特异性蛋白激酶。这种激酶特异性地与MAPK7/ERK5相互作用并被激活。这种激酶本身可以被MAP3K3/MEKK3以及非典型蛋白激酶C异构体(aPKCs)磷酸化和激活。这个激酶介导的信号级联参与生长因子刺激的细胞增殖和肌肉细胞分化。这个基因的三种可变剪接转录变异体已经描述，它们编码不同的异构体。[由RefSeq提供，2011年5月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
MAP2K5 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
