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中文人类
MAP2K1 - Mitogen-activated Protein Kinase Kinase 1
Alias:
MEL
CFC3
MEK1
MKK1
MAPKK1
PRKMK1
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这个基因编码的蛋白质是双特异性蛋白激酶家族的成员，作为有丝分裂激活蛋白（MAP）激酶激酶发挥作用。MAP激酶，也称为细胞外信号调节激酶（ERKs），作为多个生物化学信号的整合点。这个蛋白激酶位于MAP激酶的上游，并在各种细胞外和细胞内信号刺激下刺激MAP激酶的酶活性。作为MAP激酶信号转导途径的必备成分，这个激酶参与许多细胞过程，如增殖、分化、转录调节和发育。[RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
MAP2K1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
