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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
MAPK10 - Mitogen-activated Protein Kinase 10
Alias:
JNK3
JNK3A
PRKM10
SAPK1b
p493F12
p54bSAPK
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是MAP激酶家族的成员。MAP激酶作为多个生物化学信号的整合点,参与多种细胞过程,如增殖、分化、转录调节和发育。这个激酶在神经系统的一组特定神经元中特异地表达,并通过苏氨酸和酪氨酸磷酸化激活。小鼠中这个基因的定向缺失提示它可能参与应激诱导的神经元凋亡。这个基因的不同剪接转录变异体已经描述过,它们编码不同的异构体。最近的一项研究提供了这个基因中翻译读穿的证据,并通过使用一个替代的帧内翻译终止密码子表达了额外的C-末端延伸的异构体。[RefSeq,2017年12月提供]
Related ID:
NCBI:5602
ENSEMBL:ENSG00000109339
HGNC:6872
UNIPROT:P53779
OMIM:602897
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
5602
14
14
583670 bp
52.59
18
1
5
17
MAPK10 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
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Abundance
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Interactions
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Regulation
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Residues
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Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
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Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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