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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
MAPK6 - Mitogen-activated Protein Kinase 6
Alias:
ERK3
PRKM6
p97MAPK
HsT17250
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是Ser/Thr蛋白激酶家族的成员,与有丝分裂激活蛋白激酶(MAP激酶)有密切关系。MAP激酶也被称为细胞外信号调节激酶(ERKs),通过蛋白质磷酸化级联激活,并作为多个生物化学信号的整合点。这个激酶位于细胞核中,据报道,在用血清或福尔博酯处理成纤维细胞后会被激活。[由RefSeq,2008年7月提供]
Related ID:
NCBI:5597
ENSEMBL:ENSG00000069956
HGNC:6879
UNIPROT:Q16659
OMIM:602904
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
5597
13
6
95551 bp
82.68
16
--
7
14
MAPK6 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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