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中文人类
PRKCZ - Protein Kinase C Zeta
Alias:
PKC2
PKC-ZETA
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蛋白激酶C（PKC）ζ是PKC家族丝氨酸/苏氨酸激酶的一个成员，该家族的激酶参与多种细胞过程，如增殖、分化和分泌。与依赖钙的经典PKC同工酶不同，PKC ζ表现出一种独立于钙和二酰甘油但不依赖于磷酸丝氨酸的激酶活性。此外，它对典型的PKC抑制剂不敏感，不能被四环素激活。与经典PKC同工酶不同，它只有一个锌指模块。这些结构和生化特性表明，ζ亚种与PKC其他同工酶有关，但不同。替代剪接产生多个转录变体，编码不同的亚型。[由RefSeq提供，2008年7月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
PRKCZ Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
