Log In|Sign Up
中文人类
DOK5 - Docking Protein 5
Alias:
IRS6
IRS-6
C20orf180
Favorite
这个基因编码的蛋白质是DOK家族膜蛋白的一员，DOK家族是参与信号转导的适配器蛋白质。编码的蛋白质与磷酸化的受体酪氨酸激酶相互作用，调节神经突伸出和MAP激酶通路的激活。与其他DOK家族蛋白质不同，这个蛋白质不与RASGAP相互作用。这个蛋白质在系统性硬化症患者中被上调，并与胰岛素样生长因子结合蛋白5诱导的纤维化有关。这个基因的可变剪接导致多个转录变异体。[RefSeq提供，2014年6月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
DOK5 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
