人类

AXL - AXL Receptor Tyrosine Kinase

Alias:
ARK
UFO
JTK11
Tyro7
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是Tyro3-Axl-Mer(TAM)受体酪氨酸激酶亚家族的成员。编码的蛋白质具有一个细胞外结构域,该结构域由N端的两个免疫球蛋白样基序组成,后面跟着两个纤维连接蛋白型III基序。它通过结合维生素K依赖性蛋白质生长抑制特异性6(Gas6)将信号从细胞外基质传递到细胞质中。这个基因可能参与多种细胞功能,包括多种细胞类型中的生长、迁移、聚集和抗炎。编码的蛋白质作为多种病毒的宿主细胞受体,包括马尔堡、埃博拉和拉沙病毒,并且是SARS-CoV2病毒的候选受体。[由RefSeq,2021年9月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
3
20
42544 bp
98.34
155
1
10
32

AXL Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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