Log In|Sign Up
中文人类
PRKAA2 - Protein Kinase AMP-activated Catalytic Subunit Alpha 2
Alias:
AMPK
AMPK2
PRKAA
AMPKa2
Favorite
这个基因编码的蛋白质是AMP激活的蛋白激酶（AMPK）的催化亚基。AMPK是一个由alpha催化亚基、非催化性beta亚基和gamma亚基组成的三聚体。AMPK是一种重要的能量感应酶，监测细胞能量状态。响应细胞代谢压力，AMPK被激活，从而磷酸化并失活乙酰辅酶A羧化酶（ACC）和β-羟基β-甲基辅酶A还原酶（HMGCR），这些是参与调节脂肪酸和胆固醇新生合成的关键酶。小鼠对应物的研究提示，这个催化亚基可能控制全身胰岛素敏感性，并在缺血期间维持心肌能量稳态是必要的。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
PRKAA2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
