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中文人类
PRKAA1 - Protein Kinase AMP-activated Catalytic Subunit Alpha 1
Alias:
AMPK
AMPKa1
AMPK alpha 1
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这个基因编码的蛋白质属于丝/苏蛋白激酶家族。它是5'-prime-AMP-激活的蛋白激酶（AMPK）的催化亚基。AMPK是所有真核细胞中保守的细胞能量传感器。AMPK的激酶活性受到增加细胞AMP/ATP比值的刺激的激活。AMPK通过磷酸化调节许多关键代谢酶的活性。它通过关闭消耗ATP的生物合成交联途径来保护细胞免受导致ATP耗尽的应激。观察到了编码不同异构体的可变剪接转录变异体。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
PRKAA1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
