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中文人类
ZCCHC8 - Zinc Finger CCHC-type Containing 8
Alias:
PFBMFT5
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这个基因编码一个支架蛋白，作为核RNA外切体复合物的辅助因子。编码的蛋白质与hMTR4和RNA结合因子RBM7一起形成三聚体的人类核外切体靶向（NEXT）复合物，促进非编码的启动子上游转录本、增强子RNA和组蛋白和小核RNA转录的3'延伸产物的外切体降解。这个复合物还被认为通过与外切体和剪接体两者的相互作用，将外切体招募来降解内含子RNA。它包含一个N-末端锌指结构和一个C-末端富含脯氨酸的结构域。[由RefSeq，2017年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ZCCHC8 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
