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中文人类
PPP2R1B - Protein Phosphatase 2 Scaffold Subunit Abeta
Alias:
PR65B
PP2A-Abeta
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这个基因编码一个蛋白磷酸酶2的恒定调节亚单位。蛋白磷酸酶2是四种主要的Ser/Thr磷酸酶之一，与细胞生长和分裂的负调控有关。它由一个共同的异源核心酶组成，该酶由一个催化亚单位和一个恒定调节亚单位组成，并与各种调节亚单位结合。恒定调节亚单位A作为支架分子，协调催化亚单位和可变调节B亚单位的组装。这个基因编码恒定调节亚单位A的β异构体。这个基因的突变与一些肺和结肠癌症有关。已经描述了可变剪接的转录变异体。[RefSeq，2010年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
PPP2R1B Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
