Log In|Sign Up
中文人类
PRMT6 - Protein Arginine Methyltransferase 6
Alias:
HRMT1L6
Favorite
这个基因编码的蛋白质属于精氨酸N-甲基转移酶家族，它们催化S-腺苷-L-甲硫氨酸的甲基基团依次转移到蛋白质中精氨酸残基的侧链氮上，形成甲基化的精氨酸衍生物和S-腺苷-L-高半胱氨酸。这个蛋白质可以催化ω-N单甲基精氨酸和不对称二甲基精氨酸的形成，后者具有强烈的偏好。它特异地介导组蛋白H3的Arg2的不对称二甲基化，甲基化的形式代表了一种特定的表观遗传转录抑制标签。这个蛋白质还与DNA聚合酶β形成复合物并进行甲基化，从而通过增强DNA结合和进程性来刺激聚合酶活性。[RefSeq，2011年9月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
PRMT6 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
