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中文人类
ODAD2 - Outer Dynein Arm Docking Complex Subunit 2
Alias:
gudu
ARMC4
CILD23
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这个基因编码的蛋白质含有10个Armadillo重复序列(ARMs)和1个HEAT重复序列，被认为与鞭毛和纤毛的运动有关。这种蛋白质已被证明定位在呼吸细胞的鞭毛轴丝和鞭毛基部。研究表明，这个基因的突变导致呼吸鞭毛的部分外DYNEIN臂(ODA)缺陷。这个基因突变的细胞鞭毛显示鞭毛搏动频率和振幅降低，或完全不动。一些原发性气管异常(PCD)患者被证明具有这个基因的突变。PCD的特征是慢性气道疾病和左右身体不对称缺陷。可变剪接导致编码不同异型体的多种转录变异体。[由RefSeq，2015年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ODAD2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
