人类

PPP1R8 - Protein Phosphatase 1 Regulatory Subunit 8

Alias:
ARD1
ARD-1
NIPP1
NIPP-1
PRO2047
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因通过可变剪接编码三个不同的同源异型体。这个基因编码的两个蛋白质同源异型体是类型1丝氨酸/苏氨酸蛋白磷酸酶的特异性抑制剂,可以结合但不能切割RNA。第三个蛋白质同源异型体缺乏磷酸酶抑制功能,但是一种与大肠杆菌E. coli的RNase E相当的单链内切核酸酶。这个同源异型体需要镁离子才能发挥功能,并切割A+U丰富的RNA中的特定位点。[由RefSeq提供,2008年7月]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
3
7
20895 bp
38.48
8
--
3
24

PPP1R8 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
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