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中文人类
SARS2 - Seryl-tRNA Synthetase 2, Mitochondrial
Alias:
SYS
SARS
SERS
SARSM
SerRS
SerRSmt
mtSerRS
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该基因编码线粒体丝氨酸-tRNA合成酶前体，属于II类tRNA合成酶家族。成熟的酶催化丝氨酸与tRNA(丝)的连接，并参与线粒体内硒代半胱酰-tRNA(sec)的生物合成。该酶含有N-末端tRNA结合结构域和核心催化结构域。它以同源二聚体形式发挥作用，由tRNA结合稳定。该基因受双向启动子调控，也控制线粒体核糖体蛋白S12的表达。两个基因都在常染色体显性耳聋位点DFNA4的关键区段内，可能与这种疾病有关。已发现该基因有多个编码不同异型的转录变异体。[RefSeq，2009年3月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
SARS2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
