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中文人类
CKMT1A - Creatine Kinase, Mitochondrial 1A
Alias:
CKMT1
U-MtCK
mia-CK
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线粒体肌酸(MtCK)激酶负责将高能磷酸盐从线粒体转移到细胞质载体肌酸。它属于肌酸激酶同功酶家族。它以两种同功酶存在，肌节MtCK和泛在MtCK，由不同的基因编码。线粒体肌酸激酶以两种不同的寡聚形式存在：二聚体和八聚体，这与仅限于二聚体的细胞质肌酸激酶同功酶不同。许多具有不良预后恶性癌症已经显示出泛在线粒体肌酸激酶的过度表达；这可能与高能周转有关，并通过凋亡消除癌细胞失败。泛在线粒体肌酸激酶与肌节线粒体肌酸激酶的编码外显子具有80%的同源性。已经识别出位于染色体15上相互靠近的两个基因，它们编码相同的线粒体肌酸激酶蛋白质。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CKMT1A Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
