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中文人类
TRPM7 - Transient Receptor Potential Cation Channel Subfamily M Member 7
Alias:
CHAK
CHAK1
ALSPDC
LTRPC7
LTrpC-7
TRP-PLIK
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这个基因属于瞬时受体电位家族离子通道的melastatin亚家族。这个基因编码的蛋白质既是离子通道，也是丝氨酸/苏氨酸蛋白激酶。激酶活性对离子通道功能是必不可少的，其作用是增加细胞内钙离子水平，帮助调节镁离子内稳态。编码的蛋白质参与细胞骨架组织、细胞粘附、细胞迁移和器官发生。这个基因的缺陷是关岛肌萎缩侧索硬化-帕金森病/痴呆综合症的原因。这个基因可能与心脏功能缺陷有关。[RefSeq，2017年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
TRPM7 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
