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中文人类
PPARG - Peroxisome Proliferator Activated Receptor Gamma
Alias:
GLM1
CIMT1
NR1C3
PPARG1
PPARG2
PPARG5
PPARgamma
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这个基因编码一种核受体PPAR亚家族成员。PPARs与类视黄醇X受体(RXRs)形成异二聚体，这些异二聚体调节各种基因的转录。已知的PPARs有3个亚型：PPAR-alpha、PPAR-delta和PPAR-gamma。这个基因编码的蛋白质是PPAR-gamma，是脂肪细胞分化的调节因子。此外，PPAR-gamma与多种疾病的病理有关，包括肥胖、糖尿病、动脉粥样硬化和癌症。已经描述了编码不同异型体的替代剪接转录变异体。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
PPARG Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
