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中文人类
ATR - ATR Serine/threonine Kinase
Alias:
FRP1
MEC1
SCKL
FCTCS
SCKL1
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这个基因编码的蛋白质是一种丝氨酸/苏氨酸激酶和DNA损伤传感器，在DNA压力下激活细胞周期检查点信号。编码的蛋白质可以磷酸化并激活参与抑制DNA复制和有丝分裂的几个蛋白质，并可以促进DNA修复、重组和凋亡。这个蛋白质对于脆弱位点的稳定性和中心体复制也很重要。这个基因的缺陷是Seckel综合症1的原因。[由RefSeq，2017年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ATR Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
