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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
SMOX - Spermine Oxidase
Alias:
PAO
SMO
PAO1
PAOH
PAO-1
PAOH1
C20orf16
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
多胺是一类广泛存在的聚阳离子烷基胺,包括精胺、亚精胺、腐胺和胍胺。这些分子参与多种细胞功能,包括细胞周期调节、清除活性氧物种和控制基因表达。这些分子还通过调节细胞表面受体活性、参与细胞内信号通路以及作为神经递质的推测作用,在神经传递中扮演重要角色。这个基因编码一个含有FAD的酶,催化精胺氧化为亚精胺,并次要地产生过氧化氢。已经在这个基因中鉴定出多种编码不同同工酶的转录变异体,其中一些在天然多胺底物上没有显示出显著的氧化酶活性。特征的同工酶具有独特的生物化学特性和底物特异性,表明在多胺代谢中存在额外的复杂层次。[RefSeq,2012年7月提供]
Related ID:
NCBI:54498
ENSEMBL:ENSG00000088826
HGNC:15862
UNIPROT:Q9NWM0
OMIM:615854
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
54498
13
7
38900 bp
61.82
12
--
4
12
SMOX Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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Transcript
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CDS(bp)
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
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Alphabetical
Cell-specific RNA expression
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Type
Name
MGI
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Name
CAS Number
Status
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Link
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References Literature
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