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中文人类
XRN1 - 5'-3' Exoribonuclease 1
Alias:
SEP1
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这个基因编码5'-3'核酸酶家族的一员。编码的蛋白质可能涉及依赖复制的组蛋白mRNA降解，并直接与mRNA去帽蛋白4的增强子相互作用。除了mRNA代谢外，酵母中类似的蛋白质已被证明具有多种核质功能，包括同源重组、减数分裂、端粒维持和微管组装。这个基因的突变与骨肉瘤有关，表明编码的蛋白质也可能在骨形成中发挥作用。可变剪接产生多种转录变异体。[RefSeq，2013年9月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
XRN1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
