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中文人类
SSH1 - Slingshot Protein Phosphatase 1
Alias:
SSH1L
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这个基因编码的蛋白质属于调控肌动蛋白丝动态的slingshot同源(SSH)磷酸酶家族。SSH蛋白去磷酸化并激活肌动蛋白结合/解聚因子cofilin，cofilin随后结合肌动蛋白丝并刺激其解体。cofilin被激酶如LIM结构域激酶-1(LIMK1)抑制，LIMK1也可能被SSH蛋白去磷酸化并抑制。因此，SSH家族通过重活化cofilin蛋白似乎在肌动蛋白动态中发挥作用。这个基因的不同剪接转录变异体已经描述，编码不同的异构体。[RefSeq，2011年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
SSH1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
