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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Cldn6 - claudin 6
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个claudin家族的成员。Claudins是整合膜蛋白,是紧密连接链的组成部分。紧密连接链作为物理屏障,防止溶质和水分自由通过上皮或内皮细胞片之间的胞间空间。它们还在维持细胞极性和信号传导中起到关键作用。这个基因编码的蛋白质对早期小鼠胚胎着床前囊胚形成是必需的,并参与表皮通透性屏障的形成和维持。这个基因在染色体17上与另一个家族成员Cldn9相邻。[RefSeq,2010年8月提供]
Related ID:
NCBI:54419
ENSEMBL:ENSMUSG00000023906
UNIPROT:Q9Z262
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
54419
2
3
3073 bp
23.39
5
4
Cldn6 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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