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中文人类
POLR2E - RNA Polymerase II, I And III Subunit E
Alias:
RPB5
XAP4
RPABC1
hRPB25
hsRPB5
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这个基因编码RNA聚合酶II的第五大亚基，该聚合酶负责在真核生物中合成信使RNA。这个亚基被其他两个DNA导向的RNA聚合酶所共享，并以两倍摩尔过剩的形式存在于其他聚合酶亚基中。已经证明了这个亚基与肝炎病毒转激活蛋白之间的相互作用，这表明转录激活剂与聚合酶之间的相互作用可以通过这个亚基发生。一个假基因位于染色体11上。已经发现这个基因有三个转录变异体，编码两种不同的异构体。[RefSeq，2015年10月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
POLR2E Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
